diff --git a/includes/Hooks.php b/includes/Hooks.php
index 8c2cc25e0..dea89cad9 100644
--- a/includes/Hooks.php
+++ b/includes/Hooks.php
@@ -261,7 +261,8 @@ class Hooks implements
 			return;
 		}
 
-		$dbType = $updater->getDB()->getType();
+		$db = $updater->getDB();
+		$dbType = $db->getType();
 
 		$dir = dirname( __DIR__ ) . '/sql';
 
@@ -293,7 +294,48 @@ class Hooks implements
 		$updater->addExtensionTable( 'echo_push_topic', "$dir/echo_push_topic.sql" );
 
 		// 1.39
-		if ( $dbType === 'mysql' || $dbType === 'sqlite' ) {
+		if ( $dbType === 'mysql' && $db->tableExists( 'echo_push_subscription', __METHOD__ ) ) {
+			// Splitted into single steps to support updates from some releases as well - T322143
+			$updater->renameExtensionIndex(
+				'echo_push_subscription',
+				'echo_push_subscription_user_id',
+				'eps_user',
+				"$dir/$dbType/patch-echo_push_subscription-rename-index-eps_user.sql",
+				false
+			);
+			$updater->dropExtensionIndex(
+				'echo_push_subscription',
+				'echo_push_subscription_token',
+				"$dir/$dbType/patch-echo_push_subscription-drop-index-eps_token.sql"
+			);
+			$updater->addExtensionIndex(
+				'echo_push_subscription',
+				'eps_token',
+				"$dir/$dbType/patch-echo_push_subscription-create-index-eps_token.sql"
+			);
+			$updater->addExtensionField(
+				'echo_push_subscription',
+				'eps_topic',
+				"$dir/$dbType/patch-echo_push_subscription-add-column-eps_topic.sql"
+			);
+
+			$res = $db->query( 'SHOW CREATE TABLE ' . $db->tableName( 'echo_push_subscription' ), __METHOD__ );
+			$row = $res ? $res->fetchRow() : false;
+			$statement = $row ? $row[1] : '';
+			if ( str_contains( $statement, $db->addIdentifierQuotes( 'echo_push_subscription_ibfk_1' ) ) ) {
+				$updater->modifyExtensionTable(
+					'echo_push_subscription',
+					"$dir/$dbType/patch-echo_push_subscription-drop-foreign-keys_1.sql"
+				);
+			}
+			if ( str_contains( $statement, $db->addIdentifierQuotes( 'echo_push_subscription_ibfk_2' ) ) ) {
+				$updater->modifyExtensionTable(
+					'echo_push_subscription',
+					"$dir/$dbType/patch-echo_push_subscription-drop-foreign-keys_2.sql"
+				);
+			}
+		}
+		if ( $dbType === 'sqlite' ) {
 			$updater->addExtensionIndex( 'echo_push_subscription', 'eps_user',
 				"$dir/$dbType/patch-cleanup-push_subscription-foreign-keys-indexes.sql" );
 		}
diff --git a/sql/mysql/patch-cleanup-push_subscription-foreign-keys-indexes.sql b/sql/mysql/patch-cleanup-push_subscription-foreign-keys-indexes.sql
deleted file mode 100644
index d6fa63fb4..000000000
--- a/sql/mysql/patch-cleanup-push_subscription-foreign-keys-indexes.sql
+++ /dev/null
@@ -1,10 +0,0 @@
--- Drop foreign keys from echo_push_subscription - T306473
-ALTER TABLE /*_*/echo_push_subscription DROP FOREIGN KEY /*_*/echo_push_subscription_ibfk_1;
-ALTER TABLE /*_*/echo_push_subscription DROP FOREIGN KEY /*_*/echo_push_subscription_ibfk_2;
-
--- Rename index to match table prefix
-DROP INDEX /*i*/echo_push_subscription_user_id ON /*_*/echo_push_subscription;
-CREATE INDEX /*i*/eps_user ON /*_*/echo_push_subscription (eps_user);
-
-DROP INDEX /*i*/echo_push_subscription_token ON /*_*/echo_push_subscription;
-CREATE INDEX /*i*/eps_token ON /*_*/echo_push_subscription (eps_token(10));
diff --git a/sql/mysql/patch-echo_push_subscription-add-column-eps_topic.sql b/sql/mysql/patch-echo_push_subscription-add-column-eps_topic.sql
new file mode 100644
index 000000000..98b81291f
--- /dev/null
+++ b/sql/mysql/patch-echo_push_subscription-add-column-eps_topic.sql
@@ -0,0 +1,3 @@
+ALTER TABLE echo_push_subscription
+ADD COLUMN eps_topic TINYINT UNSIGNED;
+CREATE INDEX /*i*/eps_topic ON /*_*/echo_push_subscription (eps_topic);
diff --git a/sql/mysql/patch-echo_push_subscription-create-index-eps_token.sql b/sql/mysql/patch-echo_push_subscription-create-index-eps_token.sql
new file mode 100644
index 000000000..34d0f2687
--- /dev/null
+++ b/sql/mysql/patch-echo_push_subscription-create-index-eps_token.sql
@@ -0,0 +1,2 @@
+-- Rename index to match table prefix - T306473
+CREATE INDEX /*i*/eps_token ON /*_*/echo_push_subscription (eps_token(10));
diff --git a/sql/mysql/patch-echo_push_subscription-drop-foreign-keys_1.sql b/sql/mysql/patch-echo_push_subscription-drop-foreign-keys_1.sql
new file mode 100644
index 000000000..dca6b6091
--- /dev/null
+++ b/sql/mysql/patch-echo_push_subscription-drop-foreign-keys_1.sql
@@ -0,0 +1,2 @@
+-- Drop foreign keys from echo_push_subscription - T306473
+ALTER TABLE /*_*/echo_push_subscription DROP FOREIGN KEY /*_*/echo_push_subscription_ibfk_1;
diff --git a/sql/mysql/patch-echo_push_subscription-drop-foreign-keys_2.sql b/sql/mysql/patch-echo_push_subscription-drop-foreign-keys_2.sql
new file mode 100644
index 000000000..ba854360f
--- /dev/null
+++ b/sql/mysql/patch-echo_push_subscription-drop-foreign-keys_2.sql
@@ -0,0 +1,2 @@
+-- Drop foreign keys from echo_push_subscription - T306473 / T322143
+ALTER TABLE /*_*/echo_push_subscription DROP FOREIGN KEY /*_*/echo_push_subscription_ibfk_2;
diff --git a/sql/mysql/patch-echo_push_subscription-drop-index-eps_token.sql b/sql/mysql/patch-echo_push_subscription-drop-index-eps_token.sql
new file mode 100644
index 000000000..dfb1ba735
--- /dev/null
+++ b/sql/mysql/patch-echo_push_subscription-drop-index-eps_token.sql
@@ -0,0 +1,2 @@
+-- Rename index to match table prefix - T306473
+DROP INDEX /*i*/echo_push_subscription_token ON /*_*/echo_push_subscription;
diff --git a/sql/mysql/patch-echo_push_subscription-rename-index-eps_user.sql b/sql/mysql/patch-echo_push_subscription-rename-index-eps_user.sql
new file mode 100644
index 000000000..c23794dc8
--- /dev/null
+++ b/sql/mysql/patch-echo_push_subscription-rename-index-eps_user.sql
@@ -0,0 +1,3 @@
+-- Rename index to match table prefix - T306473
+DROP INDEX /*i*/echo_push_subscription_user_id ON /*_*/echo_push_subscription;
+CREATE INDEX /*i*/eps_user ON /*_*/echo_push_subscription (eps_user);